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Re:

To: "Barlas, Suna" <suna_barlas@merck.com>
Subject: Re:
From: Frank E Harrell Jr <fharrell@virginia.edu>
Date: Mon, 30 Jun 2003 11:38:18 -0400
Cc: s-news@wubios.wustl.edu
In-reply-to: <2C23DE2983BE034CB1CB90DB6B813FD606F151A6@uswpmx11.merck.com>
Organization: University of Virginia
References: <2C23DE2983BE034CB1CB90DB6B813FD606F151A6@uswpmx11.merck.com>
On Mon, 30 Jun 2003 11:23:52 -0400
"Barlas, Suna" <suna_barlas@merck.com> wrote:

> Hi all,
> 
> Does anybody have a code to compute sample size/power for a test on
> sensitivity or specificity?
> 
> Thanks,
> 
> Suna.
> 
> 
> 

Those are quantities that one very seldom tests hypotheses about but more 
typically makes estimates (point and interval) about, using standard binomial 
methods (even then, sensitivity and specificity have extremely limited utility 
in medical diagnosis).

---
Frank E Harrell Jr              Prof. of Biostatistics & Statistics
Div. of Biostatistics & Epidem. Dept. of Health Evaluation Sciences
U. Virginia School of Medicine  http://hesweb1.med.virginia.edu/biostat

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