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mixed-effects question

To: s-news@lists.biostat.wustl.edu
Subject: mixed-effects question
From: wayne king <king.812@osu.edu>
Date: Thu, 19 Jun 2003 11:01:31 -0400
User-agent: Mozilla/5.0 (X11; U; Linux i686; en-US; rv:1.2.1) Gecko/20021204
Hello list, I have two data sets with 22 subjects of one classification, and 20 subjects of another

response times were measured on each of these subjects in response to 20 items.

Initially I had thought about examining this data in a mixed-effects model where the items (20 of them) were the fixed effects and the subjects were the random effects, something like

lme(responsetime ~item, data=blah,blah,random=~subject);.

I have two problems, one I have more random effects (42 20 in one group, 22 in another) than observations and the sheer size of the data set is causing a error in the lme routine
[
"Problem in .C("mixed_loglik",: Unable to obtain requested dynamic memory, while calling subroutine mixed_loglik
Use traceback() to see the call stack" ]

One thought is I could group the 42 subjects into their two diagnostic groups which would reduce the random effects in the model, but I'm afraid that would gloss over the important issue of variability within groups. Any help?

thanks, wayne


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