How to use Jumper to perform a repeated measures nested logistic regression.
5 or 6 spotty injuries were placed in each eye of both eyes in a
animal. The animals then divided into three groups treated with drug
a, b, and control. Each injury was assigned a grade (0, 1, 2, 3) and
also measured its size 5 days late. Because the probability
development of a certain grade response in each lesion is influenced
by the group to which the lesion belongs, the animals, the eye (right
or left), and the injury spot. A nested design consists of 5 or 6
measures (injury spots) per eye within two measures (eyes) per mouse
within 4 measures (animals) per group. Since the dependent variable
(lesion grade) is ordinal with four levels,logistic regression
considering both a between-subjects design (three groups, each with 4
animals) and a within-subjects design (?) may be appropriate.
Regarding the size measurements, with a split-plot,
repeated-measures design may be appropriate.
Can these analysis be performed with JMP fit model platform? A sample
data is attached.
thanks
--
Lingyun Cheng, MD
Jacobs Retina Center at Shiley Eye Center
University of California, San Diego
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sample_data
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