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Re: baseline survival in time-dependent model

To: A.Perperoglou@lumc.nl
Subject: Re: baseline survival in time-dependent model
From: Terry Therneau <therneau@mayo.edu>
Date: Thu, 24 Oct 2002 10:00:17 -0500 (CDT)
Cc: s-news@lists.biostat.wustl.edu
Reply-to: Terry Therneau <therneau@mayo.edu>
 A Perperoglou asked:
 "after fitting a Cox time-dependent model I plot the survival function. I
know that S-plus estimates the Survival
at the mean value of the covariates, but what happens whith the time
dependent model?
What is the value of time that S-plus uses to estimate the survival
function?"

   The computation is easy, but there are several pitfalls with respect to
the interpretation or use of baseline survival curves after a Cox model
with time-dependent covariates.  See section 10.2.4 of the book by
Therneau and Grambsch for an extended discussion and examples.
        
                Terry Therneau
                


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