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Re: power in longitudinal lme

To: Bernd Puschner <bernd.puschner@bkh-guenzburg.de>
Subject: Re: power in longitudinal lme
From: Mike Babyak <mbabyak@nc.rr.com>
Date: Wed, 28 Jan 2004 08:09:25 -0500
Cc: snews <s-news@lists.biostat.wustl.edu>
In-reply-to: <JHEILOKJLDODCBAOAKDOEEHICHAA.bernd.puschner@bkh-guenzburg.de>
References: <JHEILOKJLDODCBAOAKDOEEHICHAA.bernd.puschner@bkh-guenzburg.de>
Reply-to: mbabyak@nospamnc.rr.com
User-agent: Mozilla/5.0 (Windows; U; Win98; en-US; rv:1.4b) Gecko/20030507
Try the calculator at

http://www.biostat.coph.usf.edu/research/psmgold/Power/growthpower.html

It's for the SEM type of growth curve, but might still suit your purpose.

Mike Babyak

Bernd Puschner wrote:

Dear S-Plus users,

we are planning a multicenter randomized clinical trial on the effect of a
new discharge planning protocol (primary outcome rehospitalization) in
patients suffering from schizophrenia. We will have two groups (treatment
and control) four centers and plan on five measurement points.
I plan to analyze data via lme in S-PLUS (i.e. mixed effects) and need to
conduct a power calculation for the grant application. I looked at the
S-Plus archives but found nothing directly relating to longitudinal designs.
Also the software designed by Steve Raudenbush (OpDes) or Roel Bosker (PINT)
was of no help. I was told by Steve Raudenbush that there is SAS code for
such a problem, but I do not have SAS. Did anyone ever conduct power
calulation for a mixed effects model with more than two measurement points
in S-Plus? Not really necessary to consider that it will be multi-site.

Any help would be highly appreciated.

Thanks,

Bernd Puschner

____________________________________________
Bernd Puschner
Ulm University, Department of Psychiatry II
Ludwig-Heilmeyer-Str. 2
D-89312 Guenzburg/Germany

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