| To: | Frank Lawrence <Cougar@psu.edu> |
|---|---|
| Subject: | Re: random effects |
| From: | Spencer Graves <spencer.graves@pdf.com> |
| Date: | Mon, 29 Mar 2004 10:32:01 -0800 |
| Cc: | s-news@lists.biostat.wustl.edu |
| In-reply-to: | <000001c415b3$89d78a30$641a7680@meth.hhdev.psu.edu> |
| References: | <000001c415b3$89d78a30$641a7680@meth.hhdev.psu.edu> |
| User-agent: | Mozilla/5.0 (Windows; U; Windows NT 5.0; en-US; rv:1.4) Gecko/20030624 Netscape/7.1 (ax) |
Have you consulted Pinhiero and Bates (2000) Mixed-Effects Models
in S and S-Plus (Springer)? On pp. 82-96, they discuss that very
issue. In brief, they found from simulations that 2*log(likelihood
ratio) in situations like this were well approximated by a mixtures of
two chi-square distributions. My memory of that material is that one
part is the naive chi-square that one would expect without the boundary
constraint while other(s) has(have) reduced degrees of freedom.
Pinhiero and Bates provide a insight into what occurs and why as well as
a simulation methodology for evaluating the result in a particular
context. I hope Doug or someone else will comment if I've missed or
misunderstood something here.
hope this helps.
spencer graves
Frank Lawrence wrote: When using lme to test if random effects are zero, I have used the anova function to compare two models; one representing the null hypothesis the other representing the alternative. I would like to know if use of anova is appropriate in these circumstances because I understand that the null hypothesis places the parameter of interest on the boundary of the parameter space. Respectfully, Frank R. Lawrence -------------------------------------------------------------------- This message was distributed by s-news@lists.biostat.wustl.edu. To unsubscribe send e-mail to s-news-request@lists.biostat.wustl.edu with the BODY of the message: unsubscribe s-news |
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