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paired values and covariates

To: s-news <s-news@wubios.wustl.edu>
Subject: paired values and covariates
From: asanquer@virbac.fr
Date: Tue, 23 Nov 2004 15:28:55 +0100
Hi,
I need an advice:
I would like to compare paired observations (pre- and post-treatment
measures)to a fixed value: does the change between pre and post values is
significantly higher than 50?

First I thank to use a classical paired t test, but I would like to use an
adjustment covariate (to take into account an important factor).
What is the correct method to use?

If I use an analysis of covariance:

pre = post + covariate

which part of the results will give me the answer related to the fixed
value 50?

Thanks for your replies

Annaële




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