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lme question

To: s-news@lists.biostat.wustl.edu
Subject: lme question
From: Birgit Mair <mair@slcmsr.org>
Date: Thu, 24 Feb 2005 16:49:06 +0100
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Hallo s-news,

I used lme to fit a linear mixed effects model as follows:
lme(y~ time + x2 + x3 + x4,  random= list(center=~1, pid=~time, data=work)

My qqnorm-plot is heavy tailed, because of a lot of outliers, so the residuals are not normally distributed. In Pinheiro and Bates (2000) I read that this would lead to conservative tests. One of my fixed effects has an p-value of 0.059 in the summary t-test, thus I have to exclude it from the model. Does anybody know, if there is a better test with "true" p-values or how to deal with this data?
Thank you in advance

Birgit

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