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Predicting number of replicates.

To: <s-news@lists.biostat.wustl.edu>
Subject: Predicting number of replicates.
From: "Khan, Sohail" <khan@cshl.edu>
Date: Wed, 12 Apr 2006 09:06:28 -0400
Thread-index: AcZeM3ofA/r0z1CLRyWEICRCuESxWw==
Thread-topic: Predicting number of replicates.
Dear List,

I have a basic statistical question.  However, I am not an statistician nor an 
S-PLUS expert.  I was told the following problem can be modeled in S_PLUS.

I have a data set with 3 replicates for the control and 3 replicates for 
experimental samples for a particular experiment.  I performed a t.test and 
adjusted the p. values for the false discovery rate.  Choosing a p value < 
0.05, I didn't see any significant difference between the control and the 
experimental samples.  My question is how can I take the existing data and sort 
of 'simulate" add data points so that the adjusted p values become significant 
(< 0.05). The data is follows:

C.1     C.2     C.3     E.1     E.2     E.3
9.33    8.97    9.03    10.12   9.84    9.65
7.35    6.98    7.14    8.36    9.30    9.02
......  ....... ........        ........        ....... .....   
....... ....... ........        ........        ....... ......

I thank you for any suggestions/advice...............any insight into this  
would be a great learning experience for me.

-Sohail 

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