| To: | Splus Listserv <s-news@lists.biostat.wustl.edu> |
|---|---|
| Subject: | 4PL model fitting |
| From: | Greg Tarpinian <sasprog474@yahoo.com> |
| Date: | Thu, 12 Oct 2006 17:01:35 -0700 (PDT) |
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WinXP, Splus7.
All,
I have been using the SSfpl and SSlogis self-starting functions
in the nlme library to fit 4PL and restricted 4PL models. I need
to adapt these routines to fit the alternative model
f(x) = A + (B-A)/(1 + abs(x/EC50)^C)
My Question: How do I obtain good starting values for this alternative
model?
(The pseudo-code found on pages 517 - 520 of "Mixed Effects Models in
S and Splus" is not applicable to my problem because it deals with
f(x)=A+(B-A)/(1+exp(EC50-x)/C)) which is not the same function.)
Many thanks,
Greg
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